What Does Diabetes Do?

Diabetes mellitus (pronounced /ˌdaɪ.əˈbiːtiːz/ or /ˌdaɪ.əˈbiːtɨs/; /mɨˈlaɪtəs/ or /ˈmɛlɨtəs/)?often simply referred to as diabetes?is a condition in which a person has a high blood sugar (glucose) level, either because the body doesn’t produce enough insulin, or because body cells don’t properly respond to the insulin that is produced. Insulin is a hormone produced in the pancreas which enables body cells to absorb glucose, to turn into energy. If the body cells do not absorb the glucose, the glucose accumulates in the blood (hyperglycemia), leading to vascular, nerve, and other complications.

There are many types of diabetes, the most common of which are:

Type 1 diabetes: results from the body’s failure to produce insulin, and presently requires the person to inject insulin.

Type 2 diabetes: results from insulin resistance, a condition in which cells fail to use insulin properly, sometimes combined with an absolute insulin deficiency.

Gestational diabetes: is when pregnant women, who have never had diabetes before, have a high blood glucose level during pregnancy. It may precede development of type 2 DM.

Other forms of diabetes mellitus include congenital diabetes, which is due to genetic defects of insulin secretion, cystic fibrosis-related diabetes, steroid diabetes induced by high doses of glucocorticoids, and several forms of monogenic diabetes.

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Managing Your Cholesterol

To reduce your risk of heart disease and stroke, work with your healthcare professionals to monitor and maintain healthy cholesterol levels. Even if your cholesterol levels are good now, it’s not too early to develop healthy habits that can help keep your numbers in check.

Learn Your Levels

Have your blood cholesterol checked regularly. Learn your levels and what the numbers mean.

Make A Plan

Work with your healthcare professionals to develop a treatment and prevention plan.

Prevent And Treat

Use these tips and tools for maintaining healthy cholesterol levels through lifestyle and medication, as your doctor may recommend.

Stay Informed

This site can help you and your doctor understand and address your unique cholesterol issues. Learn more about cholesterol and how it can affect your health.

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Cut Heart Risk by Eating Less Salt

Studies Show a Lower-Salt Diet Lowers Risk of Heart Disease and Stroke

By Salynn Boyles, WebMD Medical News
Reviewed By Louise Chang, MD

Even modest reductions in salt intake can dramatically lower heart disease risk, new research shows.

In an extended follow-up of two rigorously designed trials, people who reduced their dietary sodium while participating in the studies saw 25% reductions in heart disease and stroke risk 10 to 15 years later, compared with people who ate their usual diets.

Most people in the intervention arm of the studies — where participants reduced the sodium in their diet — lowered their sodium intake by 25% to 30%, researcher Nancy Cook, ScD, of Brigham and Women’s Hospital and Harvard Medical School, tells WebMD.

“This was not salt restriction, it was salt reduction,” she says. “These people ate normal diets, but we taught them how to look out for hidden salt and avoid it.”


Hidden Salt

The findings are the strongest evidence yet linking dietary salt intake to heart disease, Cook says. It is the first intervention trial to assess cardiovascular risk long term.

Participants were between the ages of 30 and 54 when recruited for the two salt-reduction studies, which were conducted between 1987 and 1995. All also had slightly elevated blood pressures, but none had heart disease at recruitment.

During the initial trials, roughly half of participants were taught to identify, select, and prepare low-salt foods and asked to reduce the salt in their diets. The rest were not asked to lower the salt in their diets. One study lasted for 18 months and the other study lasted for 36-48 months.

Ten to 15 years after the end of the original trials, participants in the intervention arms of the two studies were found to have lower cardiovascular risk and a slightly lower risk of death from all causes than participants who ate their usual diets.

“Americans consume much more sodium than is necessary, and it comes mostly from processed foods and the foods we eat in restaurants,” Cook says, adding that initiatives aimed at lowering dietary sodium will have a bigger impact if they target the food industry and not individuals.


Calling for Change

Last summer, the American Medical Association (AMA) called for a minimum 50% reduction in sodium in processed foods, fast foods, and non-fast-food restaurant meals within a decade. The group also called on the FDA to work harder to educate consumers about the health risks associated with a high-sodium diet.

Texas cardiologist J. James Rohack, MD, who was on the AMA board that issued the directives, says 150,000 lives could be saved in the U.S. annually if everyone cut their sodium consumption in half.

Most people eat much more salt than they realize, he says, because restaurant meals and processed foods have replaced home cooking in the American diet. The American Heart Association recommends that healthy adults should not exceed 2,300 milligrams of sodium a day. This is equal to about 1 teaspoon of table salt, but sodium is found in many processed and pre-packaged foods.

“The average American is eating three times as much salt as is healthy every day — the equivalent of 2 to 3 teaspoons instead of no more than 1,” he says. “The assumption tends to be, ‘If I don’t use my salt shaker much, I’m probably OK,’ but that just isn’t true.”

SOURCES: Cook, N.R. British Medical Journal online, April 19, 2007. Nancy R. Cook, ScD, associate professor, department of medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston. J. James Rohack, MD, FACC, FACP, board member, American Medical Association; director, Center for Healthcare Policy, Scott and White Health Plan. “Reducing the Population Burden of Cardiovascular Disease by Reducing Sodium Intake,” AMA publication, June 2006. American Heart Association web site.